Adaptations of maternal cardiovascular and renal physiology to pregnancy
نویسندگان
چکیده
Major cardiovascular and renal changes occur during pregnancy to ensure optimal development of the placenta and fetus, and to protect the health of the mother. These changes include increases in the cardiac output and reductions in the systemic vascular resistance and systemic blood pressure. A clear understanding of all these changes is necessary in order to understand how disruptions in the normal physiological responses to pregnancy result in pathological conditions associated with pregnancy such as pregnancy-induced hypertension and preeclampsia.
منابع مشابه
Relaxin is essential for renal vasodilation during pregnancy in conscious rats.
Marked vasodilation in the kidney and other nonreproductive organs is one of the earliest maternal adaptations to occur during pregnancy. Despite the recognition of this extraordinary physiology for over four decades, the gestational hormone responsible has remained elusive. Here we demonstrate a key role for relaxin, a member of the IGF family that is secreted by the corpus luteum in humans an...
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